Title:

The Gastrointestinal Microbiome in Infant Colic: A Scoping Review

 

Objective: 

To assess the scope of the gut microbiome and the impact of certain microbes on the pathogenesis of colic.

 

Results: 

Infants with colic have increased colonization with gas-producing bacteria, like Escherichia coli and Klebsiella, and they have lower colonization of anti-inflammatory bacteria, like Bifidobacterium and Lactobacillus.

 

Conclusion:

Disruptions to the microbiome colonization of the gastrointestinal system may lead to excess gas and inflammation that are associated with the crying of colic. This scoping review presents the collective evidence from 21 original, primary research articles on what is known about the gastrointestinal microbiome at colic onset and resolution.


Full study can be found HERE